This barrier also helps to keep the wound moist, which is essential for proper healing. When Silvadene is applied to a burn wound, it creates a barrier that helps prevent bacteria from entering the damaged skin. It is typically applied as a thin layer to the affected area, and the dressing is changed every one to three days, depending on the severity of the burn. Silvadene plays a crucial role in the management of burn wounds, effectively reducing the risk of infection and promoting healing. Burn Treatment with Silvadeneīurns can be excruciatingly painful and prone to infection. Let's take a closer look at how Silvadene is used in these medical settings. Silvadene's therapeutic applications extend beyond burns, as it is also utilized in wound care for various injuries and surgical incisions. Its ability to target a wide range of bacteria and fungi, combined with its anti-inflammatory effects, makes it an invaluable tool in the management of burn wounds. Overall, Silvadene is a versatile medication that not only fights against infections but also aids in the healing process. Silvadene helps reduce inflammation by modulating the immune response and promoting the release of anti-inflammatory mediators. Burn wounds often result in inflammation, which can delay the healing process. In addition to its antimicrobial properties, Silvadene has been found to have anti-inflammatory effects. Silvadene's silver ions have been shown to have inhibitory effects on the growth of various fungi, making it an effective treatment option for fungal infections as well. Fungi, such as Candida species, can also cause infections in burn wounds. Not only does Silvadene combat bacteria, but it also exhibits antifungal activity. By interfering with the DNA replication process, Silvadene disrupts the bacteria's ability to multiply, further reducing the risk of infection. This disruption of the bacterial cell wall integrity leads to the leakage of essential cellular components, ultimately leading to the death of the bacteria.įurthermore, Silvadene's ability to inhibit enzyme activity is crucial in preventing the bacteria from producing essential proteins necessary for their survival. The silver ions released by Silvadene penetrate the bacterial cell walls, causing structural damage and impairing their ability to function properly. When Silvadene is applied to a burn wound, it forms a protective barrier that acts as a shield against harmful microorganisms. This multifaceted approach helps prevent bacterial growth and promotes the healing of wounds. Silver ions released from the cream disrupt bacterial cell walls, inhibit enzyme activity, and interfere with the DNA replication process. The antimicrobial properties of Silvadene can be attributed to its active ingredient, silver sulfadiazine. This makes Silvadene a valuable weapon in the battle against burn-related infections. However, Silvadene's silver ions are able to penetrate the bacterial cell walls and disrupt their vital processes, rendering them unable to survive and multiply. Gram-negative bacteria, like Pseudomonas aeruginosa, are notorious for their resistance to antibiotics. Additionally, Silvadene has shown activity against several gram-positive bacteria and fungi. It is particularly effective against gram-negative bacteria, such as Pseudomonas aeruginosa, which are common culprits in burn-related infections. Silvadene is primarily used for treating and preventing infections in burn wounds. Silvadene comes to the rescue by creating an inhospitable environment for bacteria and fungi, preventing their growth and promoting healing. Burn wounds are susceptible to infections due to the compromised skin barrier and the presence of dead tissue. It is a powerful tool in the fight against infections, particularly in burn wounds. Silvadene is not just any ordinary cream. When applied to the skin, Silvadene slowly releases silver ions, which have broad-spectrum antimicrobial activity against various types of bacteria and fungi. Silvadene is a cream that contains 1% silver sulfadiazine, an antimicrobial agent that helps prevent and treat infections. Understanding Silvadene: An Overviewīefore delving into the medical uses and benefits of Silvadene, let's first understand what exactly this medication is. In this comprehensive guide, we will explore the ins and outs of Silvadene, including its uses, benefits, safety, and proper usage. It is primarily known for its antimicrobial properties, which make it an effective treatment for burns and wounds. Silvadene, also known as silver sulfadiazine, is a topical cream that has been widely used in the medical field for decades.
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She also maintains the team’s business plan and is constantly identifying new strategies to help ensure clients receive outstanding service from the team. Marci’s primary responsibilities include wealth and retirement planning, financial analysis, as well as helping to clients to achieve their financial goals. A results-driven professional, she is committed to building strong relationships with clients, colleagues and the various business units within Morgan Stanley. Marci is a Portfolio Associate at The Red Cardinal Group at Morgan Stanley with 23 years of industry experience. The Portfolio Management program is described in the applicable Morgan Stanley ADV Part 2, available at or from your Financial Advisor. The Portfolio Management program is an investment advisory program in which the client’s Financial Advisor invests the client’s assets on a discretionary basis in a range of securities. The individuals mentioned as the Portfolio Management Team are Financial Advisors with Morgan Stanley participating in the Morgan Stanley Portfolio Management program. It has been prepared solely for informational purposes only and is not an offer to buy or sell or a solicitation of any offer to buy or sell any security or other financial instrument, or to participate in any trading strategy. This material is intended only for clients and prospective clients of the Portfolio Management program. I look forward to hearing your story and learning how we can help you achieve your personal definition of financial success. We take great pride in helping our clients oversee and manage their finances, so they can take care of the people they love and spend more time pursuing the activities they enjoy. I surrounded myself with a caring and competent team of wealth management professionals who have become like family to me and my clients. Today, I am privileged to work with a small, yet select group of clients. I receive great satisfaction knowing I am making a significant impact on the quality of their lives and I often become one of the most important relationships to their families. One of the most enjoyable parts of my job is working with like-minded clients who value the level of service and skill I deliver. I’ve earned important industry designations, including Certified Financial Planner (CFP ®) and Certified Portfolio Manager ® (CPM ®), and am currently one of the top portfolio managers at Morgan Stanley. Over the years, I have built a successful practice, guiding individuals, families, business owners and local nonprofits in the achievement of their goals. It is a decision I am grateful for every day. In 1998, I made an important career decision to join the Morgan Stanley family. And while I enjoyed the excitement of being part of a successful start-up, I wanted to have a more direct impact on the quality of people’s lives. I played an important role in product research, project consulting, marketing and sales. I was one of the company’s first employees and participated in the early rise of company’s success. I first worked in Pittsburgh and was later promoted and transferred to their Houston office.Īfter Westinghouse, I joined ARGUS Financial Software. I earned a Bachelor of Science degree in Business Administration from Duquesne University and upon graduation, began my career with Westinghouse Credit Corporation as a Commercial Real Estate Loan Underwriter. Growing up in Pittsburgh, Pennsylvania, I always had an interest in the world of finance. I bring a lifetime of experience to my role as a wealth management professional. If you prefer a more straightforward approach to running Windows Steam games on your Mac without the need for a separate Windows installation, you can use a software solution like CrossOver. Step 3: Install Windows Steam Games on Mac using CrossOver We’ll cover three popular methods: using CrossOver, using Boot Camp, and using Parallels Desktop. Choose the method that suits your needs and system requirements. Now that you have a Steam account, you’re ready to move on to the next steps, which involve different software options to run Windows Steam games on your Mac. Make sure to keep your login credentials secure, as your Steam account grants access to your purchased games and saved progress. With your Steam account created, you can now log in and access the Steam store, where you can browse and purchase a vast catalogue of games. Once you’ve entered the verification code, your Steam account will be successfully created.If you don’t see the email, check your spam or junk folder. Next, complete the verification process by entering the verification code sent to your email address.After filling in the required information, click on the “I agree” button to accept the Steam Subscriber Agreement.Make sure to choose a strong password to protect your account. Fill in your preferred username, password, and email address. Once the Steam client is open, click on the “Create account” button located at the bottom of the login screen.Launch the Steam client on your Mac by double-clicking on the Steam icon in your Applications folder.The next step is to create a Steam account, which we’ll cover in the next section.īefore you can start downloading and playing Windows Steam games on your Mac, you need to create a Steam account. Now that you have successfully downloaded and installed Steam on your Mac, you’re one step closer to playing Windows Steam games. Once the installation is finished, the Steam client will automatically launch.You may be asked to choose a destination folder and agree to the terms and conditions. Follow the on-screen instructions to complete the installation.Double-click on the installer file to begin the installation process.Once the download is complete, locate the Steam installer file in your download folder, usually named “SteamSetup.exe”.Click on the “Download Steam” button to start the download process. Once on the Steam website, locate and click on the “Install Steam” button.Open your preferred web browser and go to the official Steam website at.The first step in playing Windows Steam games on your Mac is to download and install the Steam client. You only get three passes through the stock pile. Once all of the stock pile cards have been placed into the waste pile, you can click the waste pile so that the cards flip facedown back into the stock pile to be used again. The face-up card in the waste pile is considered to be a playable exposed card. You can turn over the top card of the stock pile to create a face-up waste pile. You can only use the face-up card in the waste pile.This means you can’t pick up an eight to pair with a five that is behind it-both must be exposed to be paired. Only cards that are not overlapped by cards in the row below are eligible to be paired with other exposed cards. Kings are the only cards that don’t need a pair because they are worth 13. An 8 and 5 can be paired since they equal 13 when added together. For example, a Jack paired with a 2 equals 13 because the Jack is worth 11 and equals 13 when added to 2. Remove cards by pairing them to add up to 13-except kings.The foundation pile: The foundation pile is where you place the pairs of cards or single Kings as you clear the tableau.The face-up card that is revealed can be used to make plays. The waste pile: Any cards you flip from the stock pile move face-up into the waste pile.The stock pile: The remaining cards, placed facedown, become the stock pile, which you turn over when you run out of moves on the tableau.All rows overlap the previous row slightly. The tableau: In the main area of gameplay that you’re trying to clear, you build a pyramid of face-up cards, beginning with one at the tip of the pyramid and ending with 7 cards at the base of the pyramid.Pyramid Solitaire has four basic piles or sets of piles that you use to play the game: A king needs no other cards paired with it to remove it from the pyramid. Aces are 1, number cards are their face value, and Jacks are 11, Queens are 12, and Kings are 13. ObjectiveĬlear the tableau of cards by pairing exposed cards that equal 13. You use 1 deck of cards to set up the game by building a pyramid and stock pile from which you play. Pyramid Solitaire is a unique spin on traditional Klondike Solitaire, during which you clear the tableau by pairing cards that add up to 13 instead of sequencing cards. He is helped in this by his Staff, which can either lower the cost of Creature allies by 2, making many Creatures free, but it can also ready a Creature ally or return a Creature enemy to the staging area. This gives him more uses per round, and you can play around with many different Creature allies that he can pay for. He has the ability to play Creature cards from any sphere, and does not exhaust to quest if you have played at least one Creature ally from your hand this round. The synergy of the Creature trait was introduced during the Fate of Wilderland expansion when hero Radagast was announced. Lore Creature allies are only the Loyal Hounds, who are also aggressive, and have damage cancellation options. Leadership Creature allies support your deck with some willpower, stat buffs, and a potential card draw engine. Spirit Creature cards are horses, which can either make progress on locations, or attach to other allies in order to boost their stats, turning from Creature into a Mount. Tactics Creature cards tend to be the more combat focussed allies, like Eagles and Beornings. This opens up some more card draw for you, allowing you to get your creatures out even faster! The Lore sphere is probably going to be used in such a deck, since you will likely run Radagast in his hero version. This means that you can simply throw all Creature allies you have into a deck and you will be able to pay for them. His hero version allows him to use his resources for creature allies of any sphere, and his ally version does the same. However, the sphere of the Creature ally does not often matter if you are playing with either version of Radagast. The Creature cards belong to all spheres, but Tactics really stands out due to the number of Eagle allies that also have the Creature trait. During the Land of Sorrow, we even got our very first Creature hero! These packs feature Creature characters or support the trait, pick up the bold packs first: These were often used for their synergy with other traits, such as Hobbits, Rohan, and Beornings, but can also work with each other to form a Creature deck. Many of these were Eagles, but a few other creatures also joined the roster. While the Creature synergy is relatively new, we have been getting Creature allies since before the Fate of Wilderland pack. These animals will help you by carrying your loads, send messages, or to charge into battle with you! Expansion packs The game has many creatures that help you in your quests, ranging from bears to birds to horses. There is one ring to rule them all, indeed, but who's "them"? Here's a breakdown of all the different beings in Lord of the Rings explained.It wasn’t just Men, Elves, and Dwarves that withstood Sauron and his minions during the War of the Ring, many animals also helped in order to keep their territory or to help their bipedal masters. Inspired by history, mythology, philosophy, and world religions, as well as his own experiences fighting in World War I, Tolkien drew heavily from real-life inspirations in creating his fantasy world and its citizens battle between forces of light and darkness. In fact, Tolkien's descriptions, sketches, and detailed notes are so specific he completely set up the visual adaptations to succeed onscreen, even though he never lived to actually see them. The denizens of Middle-earth, even the most marginal creatures who appear only briefly, still have an entire backstory that links with others and makes Lord of the Rings an immersive experience for readers of the books and watchers of the movies alike. J.R.R Tolkien's extensive worldbuilding in Lord of the Rings remains an incredible feat not just in the history of fantasy novels, but literature in general. Imagine if something happens to your device and you lose all your important stuff. It works with Android devices too! So, if you have friends with Android phones, you can still share stuff easily. Cross-Platform CompatibilityĪnyTrans isn’t just for iPhones and iPads. You can move your photos, videos, music, and more between your devices with just a few clicks. When you get a new iPhone or iPad, you might want to move all your old stuff to the new one. So, if you want to move things, keep them safe, and not pay anything, AnyTrans is the friend you need!ĪnyTrans Premium comes with a bunch of cool things that can help you with your iPhone or iPad. And guess what? AnyTrans has a special version that doesn’t cost money! You can use it for free and do lots of cool stuff with it. 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She says she painfully remembers how her father began molesting her when she, too, was just 5 years old.Īfter years of abuse, Rachelle's parents divorced when she was 10 years old. She grew up in the same house with the same secret shame. Rachelle, Mancuso's biological daughter, says she shares a painful bond with Masha. The house where he and Masha lived has since been sold to a new family. He also pleaded guilty to the horrible sex crimes he committed against Masha and was sentenced to serve 35 to 70 years in prison. Two years ago, Matthew Mancuso was sentenced to 15 years on federal pornography charges. Sergeant Zaglifa says that to gain proper perspective on the severity of child pornography, it's important to call them "child sex abuse images." "When those images are being made," says Sergeant Zaglifa, "that's sex abuse in progress." He offers his expert advice for how parents can protect their children: "The number one thing is: No chat rooms." Her rescue, says Sergeant Zaglifa, was an unexpected reward for what he calls the "physically and emotionally draining" work of capturing child predators. Working with other agents, he traced Mancuso's Internet address to a location near Pittsburgh, where he was later arrested.ĭuring their investigation, police officials had no way of knowing that the little girl in the photographs was Mancuso's adopted daughter. Sergeant Zaglifa says his instinct told him this man was an absolute danger to children. Posing as a pedophile, Chicago area police officer Mike Zaglifa discovered Mancuso in an online chat room. Back in the states, Masha expected a nice American home with a bedroom all her own. No phone calls were made to his ex-wife or to his biological daughter. What she didn't know was the adoption agency failed to properly check her new father's background. But nothing could have been farther from the truth. Mancuso seemed like her knight in shining armor. He visited Masha several times at the orphanage, took her to nice dinners, and bought her candy. After months of waiting, Mancuso traveled to Russia to meet his new daughter. He contacted a New Jersey adoption agency requesting information on 5-year-old Caucasian girls, and chose Masha from a videotape. Meanwhile, 41-year-old Matthew Mancuso, a divorced father in Pennsylvania, was looking for a little girl to adopt. Soon after recovering from her traumatic ordeal, Masha was sent to an orphanage where she prayed that a good family would come to rescue her. Her own mother tried to kill her when she was only 4 years old by stabbing her in the back of the neck with a kitchen knife. She was born in southern Russia to an alcoholic mother and a father she never knew. At 13 years old, Masha has already survived the unthinkable. “This new labeling allows for that.”Īnother subtle, but extremely important, change in the labeling benefits the patient even more directly. “Especially when treating people with multiple pain generators, we want to have current images to make the best therapeutic decisions,” said Dr. “It’s highly imperative that if you have therapy going on, that your device be MRI-compatible to have high-quality images,” said Dr. This limited the quality of the diagnostic images that could be taken of patients using the device. Prior to this new FDA labelling, physicians wishing to use Abbott’s proprietary BurstDR™ technology were restricted in their lead placements with regard to MRI when using the Proclaim XR SCS. In addition, decisions have to be made as to what order we treat these pain generators and how treatment of one condition may impact another.” Patients with back pain often also have neck pain, headaches or arthritis and vets can have PTSD (post-traumatic stress disorder), so it can be difficult to separate out what is going on. “These people, rather than having a single source of pain that we can focus all our efforts on, are dealing with a far more complex situation. Seventy percent of our patients are active military or veterans and that population, as well as those patients entering their sixth decade, are more likely to have multiple pain generators, making MRI’s a regular part of clinical care. “Being able to get consistent MRI images is very important, especially in our practice. “I’m excited about this MRI compatibility announcement,” said Dr. Getting a Clear Look at a Complex Problem The team partners with companies, like Abbott, to determine what are the best new software designs and waveforms to treat people with intractable, chronic pain. Mehta is an interventional pain specialist who treats back, neck and head pain, while also running a research department that evaluates new therapies. Pankaj Mehta, Medical Director, Chief Medical Officer and Director of Research at Pain Specialists of America. In addition to clearing the path for more frequent MRIs, complex scans over 30 minutes will be faster due to reduced down time between scans. This announcement may sound like some minor tech improvement but it’s actually a pretty big deal.īecause pain patients and physicians know all-too-well the important role that high-quality imaging afforded by MRIs plays in their world, this opens new possibilities for improving diagnostic quality as well as patient comfort. These electrically insulated wires transmit electrical impulses to the nerves targeted by the neuromodulation device. The focus is on enhancing patient care without having to replace implanted devices.Ībbott recently received new FDA-approved labeling which expands MRI compatibility with the leads used on the Proclaim TM XR Spinal Cord Stimulation System. We are building a neuromodulation platform that offers ongoing improvement designed to continually upgrade products for our patients – past, present, and future. As recently highlighted in CEO Robert Ford’s keynote address at the 2022 CES event, Abbott is focused on remaining a leader in medical technology, continually building on a vision that will enhance patient care.Ī vital component of that vision is improving experiences for both patient and physician. I couldn't sleep because my leg felt like it was being crushed in a vise and every step I took felt like a hammer hitting my leg,” you know you are dealing with a cruelly heightened state of existence.Īnd when that same person describes his pain relief after implantation of Abbott's Proclaim™ XR SCS (spinal cord stimulation) as allowing him the opportunity to have the moments raising his two-year-old daughter that he thought he’d, “lost forever,” the stakes are clearly illuminated. Not just for this patient, but for the approximately 20% of all Americans who live with debilitating chronic pain.īut, while life-altering improvements can occur when Abbott’s neuromodulation devices are activated, these dramatic changes are far from the end of the story. When a patient-a Marine no less-describes his day-to-day as, ”Any contact with water, regardless of temperature, felt like daggers. The world of chronic pain is one that tends to lack subtlety. |
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